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  • Seung Youn Hong
  • Research Fellow

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  • Florian Felix MULKS
  • Research Fellow

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  • Heejung Chun
  • Senior Researcher
  • Reactive astrocyte, Neurodegeneration, Oxidative stress, glia-neuron interaction
  • hjcibs.re.kr

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  • EDUCATION

    Undergraduate, 2001/3~2005/2, Biological Sciences, Korea University

    Graduate, 2005/8~2015/8, Interdisciplinary Program in Neuroscience, Seoul National University

    RESEARCH EXPERIENCES

    2010/7~2014/06, Researcher, KIST

    2014/07~2015/6, Visiting Graduate student, KIST

    2016/7-present, Post doctoral fellow, KIST

    EXPERICENED RESEARCH SKILLS

    Slice Patch (Neuron and Astrocyte), Immunohistochemistry, Confocal imaging, Behavioral Test (passive avoidance test, open field test, fear conditioning, elevated plus maze), Molecular Biological Techniques (Cloning, Subcloning and RT-PCR), Stereotaxic Surgery, Cell Culture (Primary astrocyte, Primary neuron, and Cell line)

    PUBLICATIONS

    1. Channel-mediated astrocytic glutamate modulates hippocampal synaptic plasticity by activating postsynaptic NMDA receptors. Park H, Han KS, Seo J, Lee J, Dravid SM, Woo J, Chun H, Cho S, Bae J, An H, Koh W, Yoon BE, Berlinguer-Palmini R, Mannaioni G, Traynelis SF, Bae Y, Choi SY, Lee C. Mol Brain. 2015 Feb 3;8(1):7 2. Glial GABA, synthesized by monoamine oxidase B, mediates tonic inhibition Bo-Eun Yoon, JunsungWoo, Ye-Eun Chun, Heejung Chun, Seonmi Jo, Jin Young Bae, Heeyoung An, JooOkMin, Soo-Jin Oh, Kyung-Seok Han, Hye Yun Kim, Taekeun Kim, Young Soo Kim, Yong Chul Bae and C. Justin Lee. J Physiol. 2014 Sep 19. 3. GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease, Seonmi Jo, Oleg Yarishkin, Yu Jin Hwang, Ye Eun Chun, Mijeong Park, Dong Ho Woo, Jin Young Bae, Taekeun Kim, Jaekwang Lee, Heejung Chun, Hyun Jung Park, Da Yong Lee, Jinpyo Hong, Hye Yun Kim, Soo-Jin Oh, Seung Ju Park, Hyo Lee, Bo-Eun Yoon, YoungSoo Kim, Yong Jeong, Insop Shim, Yong Chul Bae, Jeiwon Cho, Neil W Kowall, Hoon Ryu, Eunmi Hwang, Daesoo Kim & C Justin Lee Nat Med. 2014 Jun 29. 4. AU-rich element-binding protein negatively regulates CCAAT enhancer-binding protein mRNA stability during long-term synaptic plasticity in Aplysia. Lee YS, Choi SL, Jun H, Yim SJ, Lee JA, Kim HF, Lee SH, Shim J, Lee K, Jang DJ, Kaang BK. Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15520-5. Epub 2012 Sep 4. 5. PKA-activated ApAF-ApC/EBP heterodimer is a key downstream effector of ApCREB and is necessary and sufficient for the consolidation of long-term facilitation. Lee JA, Lee SH, Lee C, Chang DJ, Lee Y, Kim H, Cheang YH, Ko HG, Lee YS, Jun H, Bartsch D, Kandel ER, Kaang BK. J Cell Biol. 2006 Sep 11;174(6):827-38. 6. Regulation of ApC/EBP mRNA by the Aplysia AU-rich element-binding protein, ApELAV, and its effects on 5-hydroxytryptamine-induced long-term facilitation. Yim SJ, Lee YS, Lee JA, Chang DJ, Han JH, Kim H, Park H, Jun H, Kim VN, Kaang BK. J Neurochem. 2006 Jul;98(2):420-9. 7. SALM synaptic cell adhesion-like molecules regulate the differentiation of excitatory synapses.Ko J, Kim S, Chung HS, Kim K, Han K, Kim H, Jun H, Kaang BK, Kim E. Neuron. 2006 Apr 20;50(2):233-45.

  • Min-ho Nam
  • Research fellow
  • MD (Korean Medicine), PhD from Kyung Hee University
  • dr.namminhogmail.com

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  • Education

    2013.03 – 2017. 02 Ph.D. from College of Korean Medicine, Kyung Hee University 
    Advisor: Kwang Seok Ahn, Bum Sang Shim 
    Mentor: Justin C. Lee (Korea Institute of Science and Technology) 
    Honors: 1st prize of oral presentation at annual workshop of Brain Science Institute, KIST (2014), Poster award at 2015 Glia Meeting Korea (2015), Poster award at Brain conference 2015 (2015), 2nd prize of oral presentation at KIST Junior R&D Expo (2016), Poster award at 2017 Glia Meeting Korea (2017)

    2011.03 – 2013.02 M.S. from College of Korean Medicine, Kyung Hee University 
    Advisors: Kwang Seok Ahn, Seung-Hoon Choi 
    Mentor: Kwang-Sup Soh (Seoul National University) 
    Thesis: Investigation of the primo vascular system underneath the superior sagittal sinus in the brain 
    Honors: Korea Junior Research Fellowship (2012~2015)

    2004.03 - 2011.02 MD (Korean Medicine) and B.S. from College of Korean Medicine, Kyung Hee University 
    Honors: Youth Heojun Award (2010), Korea Presidential Youth Talent Award (2010), Dean's honored graduate (2011)

    2001.03 - 2004.02 Korean Minjok Leadership Academy (민족사관고등학교)


    Experience 
    Center for glia-neuron interaction, Brain Science Institute, Korea Institute of Science and Technology 
    Post-doc, 2017.03 – present

    Lab for glia-neuron interaction, Center for Neural Science and Center for Functional Connectomics Center, Korea Institute of Science and Technology 
    Visiting graduate student, 2013.03 – 2017.02

    Nano Primo Research Center, Advanced Institute of Convergence Technology, Seoul National University 
    Visiting graduate student, 2011.03 – 2013.02

    Department of Pathology, College of Korean Medicine, Kyung Hee University 
    Research assistant, 2011.03 - 2012.03

    Biomedical Physics Laboratory, College of Physics & Astronomy, Seoul National University 
    Researcher, 2011.01 - 2011.02


    Publications – papers

    Lee SW*, Nam MH*, Lee BC, Herbal Acupuncture for Type 2 Diabetes: A Systematic Review, Experimental and Therapeutic Mededicine, 2017, accepted

    Nam MH, Jung SJ, Lim J, Seo E, Lim J, Lee SJ, Yoon SZ, Soh KS, A novel fibrous duct structure in the brain meninges discovered using polarized light microscopy, Journal of Korean Physical Studies, 2016;68(10):1246-53.

    Nam MH*, Lee SW*, Na HY, Yoo JH, Paik SH, Ahn KS, Ahn YM, Ahn SY, Choi SH, Lee BC, Herbal Acupuncture for the Treatment of Obesity, Journal of Acupuncture & Meridian Studies, 2016, 9(2):49-57.

    Kim J, Stefanov M, Nam MH, Kim S, Tracing Mercox Injected at Acupuncture Points under the Protocol of Partial Body Macerations in Mice, Journal of Acupuncture & Meridian Studies, 2015;8(6):314-20.

    Nam MH, Ahn KS, Choi SH. Acupuncture: A potent tool for inducing adult neurogenesis, Neural Regeneration Research, 2015;10(1):33-35.

    Nam MH*, Baek M*, Lim J, Lee S, Yoon J, Kim J, Lee MS, Soh KS. Discovery of a novel fibrous tissue in the spinal pia mater by polarized light microscopy, Connective Tissue Research, 2014;55(2):147–155.

    M. Stefanov, M. Potroz, J. Kim, J Lim, Richard Cha, MH Nam. The Primo Vascular System as a New Anatomical System, Journal of Acupuncture & Meridian Studies, 2013;6(6):331-338.

    SJ Jung, KH Bae, MH Nam, HM Kwon, YK Song, KS Soh, Primo Vascular System Floating in Lymph Ducts of Rats, Journal of Acupuncture & Meridian Studies, 2013;6(6):306-318. (Featured article)

    Nam MH, Ahn KS, Choi SH. Acupuncture stimulation induces neurogenesis in adult brain, International Review of Neurobiology, 2013;111:67-90.

    Lee SH, Bae KH, Kim GO, Nam MH, Choi YB, Kwon HM, Ryu Y, Soh KS. Primo vascular system in the lymph vessel from the inguinal to the axillary nodes, Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 472704, 6 pages, 2013. doi:10.1155/2013/472704.

    Bae KH, Park SH, Lee BC, Nam MH, Yoon JW, Kwon HM, Yoon SZ. Novel threadlike structures may be present on the large animal organ surface: evidence in swine model, Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 758763, 5 pages, 2013. doi:10.1155/2013/758763.

    Stefanov M, Kim JD, Nam MH, Soh KS. New approach of corrosion casting using direct injection of mercox into the parenchyma of different organs, The Anatomical Record, 2013;296:724–725.

    Nam MH, Lim J, Choi SH, Kim SC, Soh KS. A primo vascular system underneath the superior sagittal sinus in the brain of a rabbit, Journal of Acupuncture & Meridian Studies, 2012;5(5):210-217.

    Nam MH, Choi SH, Soh KS. Light and primo vascular system in the brain, Journal of the Korean Physical Society, 2012;60(6):903-906.

    Nam MH, Yin CS, Choi SH, Soh KS. Adult neurogenesis and acupuncture stimulation at ST36, Journal of Acupuncture & Meridian Studies, 2011;4(3):153-158.

    Nam MH, Kim Y, Kim H, Park J, Yeh HY, Lee YS, Lee S, Jung WM, Hong YK, Lee H, Park HJ, Chae Y, A Comparison Study of Factors of Willingness to Use Traditional Medicine between Korean, Chinese and Taiwanese, J Korean Oriental Med 2011;32(1):36-55.

    Kim SY, Kim H, Nam MH, Li Y, Chung HC, Park HJ, Lee H, Chae Y, Evaluation of a Traditional Korean Medicine Content Factor and Satisfaction with the Drama ‘Daejanggeum’, The Journal of Korean Acupuncture & Moxibustion Society, 2010;27(1):11-20.