Center for Relativistic Laser Science

      IBS Center for Molecular Spectroscopy and Dynamics

■        SPEAKER
Prof. Francois Amblard (School of Life Sciences UNIST)

■        TITLE
Why does Dynamics Matter for Molecules and Cells? 

    Optical & biological investigations of structural dynamics and transport

■        ABSTRACT
Cells assemble building blocks molecules to produce highly dynamic structures across scales. I will try to articulate what dynamics can possibly mean at different scales and how dynamic properties could ultimately determine biological functions. Over the years we focused on cytoskeleton dynamics and will first report on how actin self-assembly dynamics can produce defective polymerization intermediates and lead to kinetic control of structures. I will then describe how we used the outstanding sensitivity of multiple light scattering to resolve the non-thermal fluctuations induced by motor proteins in actin-myosin networks. We observed anisotropic effective temperatures and quantitatively described the conformational dynamics of the myosin powerstroke. Finally at the multicellular scale I will briefly report on E-cadherin turnover at intercellular junctions and demonstrates how it serves the purpose of the dynamic stabilization of cell-cell adhesion.

■        DATE AND VENUE
July 13 2017 (Thursday 11:00 - 12:00)  

Seminar Room 116 KU R&D Center

■        LANGUAGE
English

■        INVITED BY
Prof. Sang -Hee Shim

* If you want to discuss with Prof. Francois Amblard or have a lunch with him please contact to Prof. Sang-Hee Shim (sodaus@gmail.com).