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IBS-CMSD Colloquium_Prof. Haw Yang (Princeton University)(June 27)

작성자 : Center for Molecular Spectroscopy and Dynamics 등록일 : 2017-06-09 조회수:8064

       

  IBS Center for Molecular Spectroscopy and Dynamics

 

COLLOQUIUM

 

   SPEAKER
Prof. Haw Yang (Princeton University)

 

   TITLE
The Configurational and Kinetic Elements of Molecular Dynamics in Complex Systems

 

   ABSTRACT
The distribution of the molecular property and the dynamics thereof are the two unique pieces of information enabled by the single-molecule approach but not available from the conventional ensemble-averaged experiments. In this presentation, we will discuss how single-molecule Förster-type resonance energy transfer (FRET) helps to illuminate several fundamental aspects of biochemistry and molecular biology. Ideas that will be examined include the basic notion of the venerable “induced-fit” concept, conformational gating, and the molecular nature of cooperativity. We next discuss how the application scope can be expanded to visualizing a virus-like nanoparticle—and eventually a single HIV-1 virus—approaching a living cell in real time and in full 3D fidelity (3D multi-resolution imaging). We will also point out the technologies and the theoretical underpinning that made possible these experiments and quantitative interpretation thereof.

 

   DATE AND VENUE
June 27, 2017 (Tuesday, 4:00 - 5:00 p.m.)

Seminar Room 116, KU R&D Center

 

   LANGUAGE
English

 

   INVITED BY
Prof. Sang-Hee Shim

 

 

      * If you want to discuss with Prof. Haw Yang (from 1 to 4 pm) or have a dinner with him, please contact to Prof. Sang-Hee Shim (sangheeshim@korea.ac.kr).