Center for Relativistic Laser Science

        IBS Center for Molecular Spectroscopy and Dynamics

• SPEAKER
  Dr. Yookyung Jung (Harvard Medical School)
  

• TITLE
  Application of Optical Microscopy from Nanomaterials to Live animals
  

• ABSTRACT
  My previous research achievements about nano-photonnics and bio-imaging will be summarized in this presentation. The biomedically important applications of the label-free optical imaging methods such as optical coherence tomography (OCT) and coherent anti-Stokes Raman scattering (CARS) microscopy will be introduce shortly. Main focus of the presentation will be the application of the video-rate intravital optical microscopy to the mouse bone marrow. In particular, the permeability of the blood vessels in the mouse bone marrow will be discussed. Understanding the permeability of the blood vessels in the bone marrow is important because it is highly related with the ability to transport cells, molecules, nutrients, or oxygen in and out of the surrounding tissue. However, the accurate measurement of the permeability of the vessels in the bone marrow has been challenging due to the high permeability and the proximity of the micrometer-size vessels. In this presentation, I visualize the microvasculature in bone marrow in vivo by combining the customized video rate confocal, multiphoton microscopy and the surgery of opening the scalp of a mouse for optical access to the underlying dorsal skull surface. Fast, video rate microscopy enabled the accurate measurement of permeability at early time point after the vasculature dye injection before retention of dye occurs in the tissue. I will finish the presentation with the research plans for the deep tissue and label-free optical microscopy. These will cover the application of the laser ablation, in vivo flow cytometry, and the oblique back illumination microscopy (OBM).
  

• DATE AND VENUE
  June 5, 2017 (Monday, 5:00-6:00 p.m.)    /Seminar Room 116, KU R&D Center
  

• LANGUAGE
  English/Korean

   

• INVITED BY
  Associate Director Wonshik Choi 

      * Dr. Yookyung Jung will be joining IBS CMSD as a YSF(Young Scientist Fellow) researcher from September 2017. If you want to discuss with Dr. Yookyung Jung (from 3 to 5 pm) or have a dinner with him, please contact to Dr. Seokchan Yoon (sdlkfwpeorup@gmail.com).