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Interferometric scattering microscopy: The new technique for label-free live cell imaging ABC 2018 Interferometric scattering (iSCAT) microscopy is the new label-free optical imaging technique, originally developed to track a very weak light signal scattered from nano-biomolecules at an ultrahigh spatial and temporal resolution. Here, as a new application of iSCAT, we report on the iSCAT live cell imaging which reveals the underlying stru... RegDate 2020-03-26 Hit 1973
Focusing of light energy inside scattering media by controlling the time-gated multiple light scattering ABC 2018 Delivering light energy into the target object embedded in scattering media is critical for optical imaging or sensing. However, only a small fraction of incident waves reaches the target object due to random diffusion. Here we present a method to enhance light energy delivery toward the deeply embedded target in scattering media. With the im... RegDate 2020-03-26 Hit 1772
The long-range correlations of time-resolved speckle patterns ABC 2018 Abstract: Recently we were able to deliver light energy to the objects embedded in a disordered medium by coupling incident light into time-resolved reflection eigenchannels that control the transmittance or reflectance due to the interference between waves experiencing multiple scattering in disordered media. It is well known that the long-r... RegDate 2020-03-26 Hit 1912
Space gating for multiple scattering suppression: a step toward deep-tissue phase imaging ABC 2018Conventional imaging scheme, relying on a ballistic wave, is severely compromised when applied to a multiply scattering medium. To mitigate the effect, a typical approach has been to distinguish and reject a multiply scattered wave in a time domain using a time-gating and/or coherence-gating method. Here, we present a new gating scheme based o... RegDate 2020-03-26 Hit 1656
High-resolution adaptive optical imaging within scattering media using point-illumination based closed-loop accumulation of single scattering microscopy ABC 2018 Abstract: We present an adaptive optical label-free reflection microscopy that is based on the aberration correction algorithm using closed-loop accumulation of single scattering [Nature Comm. 8, 2157 (2017)], but its imaging configuration relies on the point illumination and the wide-field detection, which can make a full use of a spatial d... RegDate 2020-03-26 Hit 1745
Label-free deep-tissue imaging in vivo using adaptive optical coherence microscopy ABC 2018 Coherent optical imaging has been a useful tool for imaging of living biological subject, but its applicability has been limited to the superficial layers or early developmental stages due to the specimen-induced aberration and multiple light scattering. We propose label-free adaptive optical coherence microscopy free from hardware feedback.... RegDate 2020-03-26 Hit 1742
High-resolution and label-free neuroimaging of a living zebrafish by simultaneous angular scanning microscopy ABC 2018 We reported methods termed collective accumulation of single scattering (CASS) microscopy and closed-loop accumulation of single scattering (CLASS) microscopy. However, its application to in vivo imaging has remained unrealistic so far to the long acquisition time of the time-gated reflection matrix, a unique matrix containing wide-field and ... RegDate 2020-03-26 Hit 1619
Characterization of single photon frequency comb generated by stimulated parametric down conversion OPC 2018 Abstract― The characterization of single photon frequency comb was confirmed by the properties of generated signal photons and the second order correlation function of them depended on injection of pump and seed laser. I. IntroductionRecently, we demonstrated the frequency comb single-photon interferometry, which provided an attractive pl... RegDate 2020-03-26 Hit 1803
Spectroscopic Analysisof Photo-Degradation Process of PTB7-Th 2018 JKW Symposium There has been intensive interest in Organic photovoltaic (OPV) due to various advantages such as processability, flexibility, and low price compared with silicon based solar cell. In spite of these merits, due to its organic origin, there is an obstacle that OPV should overcome: Stability. There are various factors that affect the... RegDate 2020-03-26 Hit 1837
Spectral modulation of stimulated Raman scattering signal: Beyond weak Raman pump limit ICORS 2018 Stimulated Raman scattering has been used in label-free Raman imaging studies of live cells[1,2]. Important attempts to develope super-resolution Raman imaging with intense Raman pump or decoherence beam have been made. However, the intense beams beyond weak stimulated Raman scattering limit could complicate spectral characteristics of Raman g... RegDate 2020-03-25 Hit 2026
Fluorescence enhancement of a ligand-activated fluorescent protein induced by the collective noncovalent interactions 2018 GRC Abstract The UnaG protein and its a series of mutants can generate fluorescence through binding a ligand and its ligand binds to the protein through many noncovalent interactions. Although a difference between wild type and mutants is only single residue on N-terminus, they show significantly big change of fluorescence intensity. To elucidate... RegDate 2020-03-25 Hit 1719
Dual Frequency-Comb Transient Absorption Measurment Covering a Broad Dynamic Range UP 2018 Abstract: We present a dual frequency comb transient absorption (DFC-TA) technique that does not rely on mechanical-time-delay scan. DFC-TA measures photo-physical or -chemical processes occurring in several nanoseconds with femtosecond time resolution and millisecond data-acquisition time. Optical frequency comb (OFC) has brought a remarkable adv... RegDate 2020-03-25 Hit 1924

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